Gene basic information
| LiverAtlas Gene ID |
HuLG003404 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PCNA |
|
Synonyms |
MGC8367 |
|
Gene name |
proliferating cell nuclear antigen |
|
Gene Type |
protein-coding |
|
Chromosome |
20 |
|
Genomics Location |
20pter-p12 |
|
Known cancer genes |
Yes |
|
Protein products |
Proliferating cell nuclear antigen Proliferating cell nuclear antigen Proliferating cell nuclear antigen Proliferating cell nuclear antigen |
|
Related liver disease name |
Liver fibrosis and liver cirrhosis |
|
Database cross reference |
HGNC:8729
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0000083 |
regulation of transcription involved in G1/S phase of mitotic cell cycle |
|
GO:0000084 |
S phase of mitotic cell cycle |
|
GO:0000278 |
mitotic cell cycle |
|
GO:0000307 |
cyclin-dependent protein kinase holoenzyme complex |
|
GO:0000701 |
purine-specific mismatch base pair DNA N-glycosylase activity |
|
GO:0000722 |
telomere maintenance via recombination |
|
GO:0000723 |
telomere maintenance |
|
GO:0003677 |
DNA binding |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005634 |
nucleus |
|
GO:0005652 |
nuclear lamina |
|
GO:0005654 |
nucleoplasm |
|
GO:0005663 |
DNA replication factor C complex |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0006260 |
DNA replication |
|
GO:0006271 |
DNA strand elongation involved in DNA replication |
|
GO:0006275 |
regulation of DNA replication |
|
GO:0006281 |
DNA repair |
|
GO:0006283 |
transcription-coupled nucleotide-excision repair |
|
GO:0006284 |
base-excision repair |
|
GO:0006287 |
base-excision repair, gap-filling |
|
GO:0006289 |
nucleotide-excision repair |
|
GO:0006297 |
nucleotide-excision repair, DNA gap filling |
|
GO:0006298 |
mismatch repair |
|
GO:0006886 |
intracellular protein transport |
|
GO:0007507 |
heart development |
|
GO:0008283 |
cell proliferation |
|
GO:0015630 |
microtubule cytoskeleton |
|
GO:0019985 |
translesion synthesis |
|
GO:0030337 |
DNA polymerase processivity factor activity |
|
GO:0032077 |
positive regulation of deoxyribonuclease activity |
|
GO:0032139 |
dinucleotide insertion or deletion binding |
|
GO:0032201 |
telomere maintenance via semi-conservative replication |
|
GO:0032405 |
MutLalpha complex binding |
|
GO:0033993 |
response to lipid |
|
GO:0043596 |
nuclear replication fork |
|
GO:0043626 |
PCNA complex |
|
GO:0046686 |
response to cadmium ion |
|
GO:0048015 |
phosphatidylinositol-mediated signaling |
|
GO:0070557 |
PCNA-p21 complex |
