Gene basic information
| LiverAtlas Gene ID |
HuLG003452 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PDPK1 |
|
Synonyms |
MGC20087|MGC35290|PDK1|PRO0461 |
|
Gene name |
3-phosphoinositide dependent protein kinase-1 |
|
Gene Type |
protein-coding |
|
Chromosome |
16 |
|
Genomics Location |
16p13.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:8816
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004676 |
3-phosphoinositide-dependent protein kinase activity |
|
GO:0005158 |
insulin receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005654 |
nucleoplasm |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006469 |
negative regulation of protein kinase activity |
|
GO:0006972 |
hyperosmotic response |
|
GO:0007268 |
synaptic transmission |
|
GO:0007596 |
blood coagulation |
|
GO:0008286 |
insulin receptor signaling pathway |
|
GO:0016023 |
cytoplasmic membrane-bounded vesicle |
|
GO:0016301 |
kinase activity |
|
GO:0016310 |
phosphorylation |
|
GO:0018107 |
peptidyl-threonine phosphorylation |
|
GO:0019901 |
protein kinase binding |
|
GO:0030036 |
actin cytoskeleton organization |
|
GO:0030168 |
platelet activation |
|
GO:0031295 |
T cell costimulation |
|
GO:0032148 |
activation of protein kinase B activity |
|
GO:0032869 |
cellular response to insulin stimulus |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0048015 |
phosphatidylinositol-mediated signaling |
|
GO:0048041 |
focal adhesion assembly |
|
GO:0050852 |
T cell receptor signaling pathway |
|
GO:0090004 |
positive regulation of establishment of protein localization in plasma membrane |
