Gene basic information
| LiverAtlas Gene ID |
HuLG003478 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ATP8B1 |
|
Synonyms |
ATPIC|BRIC|FIC1|PFIC|PFIC1 |
|
Gene name |
ATPase, aminophospholipid transporter, class I, type 8B, member 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
18 |
|
Genomics Location |
18q21-q22|18q21.31 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:3706
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0000287 |
magnesium ion binding |
|
GO:0004012 |
phospholipid-translocating ATPase activity |
|
GO:0005524 |
ATP binding |
|
GO:0005624 |
membrane fraction |
|
GO:0005886 |
plasma membrane |
|
GO:0005887 |
integral to plasma membrane |
|
GO:0006200 |
ATP catabolic process |
|
GO:0006754 |
ATP biosynthetic process |
|
GO:0008206 |
bile acid metabolic process |
|
GO:0015662 |
ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism |
|
GO:0015721 |
bile acid and bile salt transport |
|
GO:0015914 |
phospholipid transport |
|
GO:0016324 |
apical plasma membrane |
|
GO:0016787 |
hydrolase activity |
|
GO:0016820 |
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances |
|
GO:0016887 |
ATPase activity |
|
GO:0034220 |
ion transmembrane transport |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0055085 |
transmembrane transport |
