HuLG003479

Entrez Gene ID

5207

Official Gene Symbol

PFKFB1

Synonyms

F6PK|HL2K|MGC116715|MGC116717|PFRX

Gene name

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xp11.21

Known cancer genes

Yes

Protein products

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

6-phosphofructo-2-kinase/fructose-2, 6-biphosphatase 1

Database cross reference

HGNC:8872
MIM:311790
Ensembl:ENSG00000158571
HPRD:02411
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

GO annotation

GO:0000166

nucleotide binding

GO:0003873

6-phosphofructo-2-kinase activity

GO:0004331

fructose-2,6-bisphosphate 2-phosphatase activity

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005829

cytosol

GO:0005975

carbohydrate metabolic process

GO:0006003

fructose 2,6-bisphosphate metabolic process

GO:0006006

glucose metabolic process

GO:0006094

gluconeogenesis

GO:0006096

glycolysis

GO:0006112

energy reserve metabolic process

GO:0007243

intracellular protein kinase cascade

GO:0016301

kinase activity

GO:0016740

transferase activity

GO:0016787

hydrolase activity

GO:0019900

kinase binding

GO:0031100

organ regeneration

GO:0032868

response to insulin stimulus

GO:0033133

positive regulation of glucokinase activity

GO:0033762

response to glucagon stimulus

GO:0042594

response to starvation

GO:0042802

identical protein binding

GO:0043540

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 complex

GO:0046835

carbohydrate phosphorylation

GO:0051384

response to glucocorticoid stimulus

GO:0051591

response to cAMP

GO:0070095

fructose-6-phosphate binding