Gene basic information
| LiverAtlas Gene ID |
HuLG003485 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PFKM |
|
Synonyms |
GSD7|MGC8699|PFKN1|PFK1|PFKA|PFKX |
|
Gene name |
phosphofructokinase, muscle |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q13.3 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:8877
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0003872 |
6-phosphofructokinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005529 |
sugar binding |
|
GO:0005625 |
soluble fraction |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0005945 |
6-phosphofructokinase complex |
|
GO:0005975 |
carbohydrate metabolic process |
|
GO:0006002 |
fructose 6-phosphate metabolic process |
|
GO:0006006 |
glucose metabolic process |
|
GO:0006096 |
glycolysis |
|
GO:0008022 |
protein C-terminus binding |
|
GO:0016208 |
AMP binding |
|
GO:0016301 |
kinase activity |
|
GO:0016324 |
apical plasma membrane |
|
GO:0016740 |
transferase activity |
|
GO:0019900 |
kinase binding |
|
GO:0030388 |
fructose 1,6-bisphosphate metabolic process |
|
GO:0032024 |
positive regulation of insulin secretion |
|
GO:0042593 |
glucose homeostasis |
|
GO:0042802 |
identical protein binding |
|
GO:0046716 |
muscle cell homeostasis |
|
GO:0046872 |
metal ion binding |
|
GO:0051259 |
protein oligomerization |
|
GO:0051289 |
protein homotetramerization |
|
GO:0070061 |
fructose binding |
|
GO:0070095 |
fructose-6-phosphate binding |
