Gene basic information
LiverAtlas Gene ID |
HuLG003502 |
Entrez Gene ID |
|
Official Gene Symbol |
ABCB1 |
Synonyms |
ABC20|CD243|CLCS|GP170|MDR1|MGC163296|PNGP|PGY1 |
Gene name |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
Gene Type |
protein-coding |
Chromosome |
7 |
Genomics Location |
7q21.12 |
Known cancer genes |
Yes |
Protein products |
ATP-binding cassette, sub-family B (MDR/TAP), member 1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
Related liver disease name |
Liver fibrosis and liver cirrhosis |
Database cross reference |
HGNC:40
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net OncoDB |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0000139 |
Golgi membrane |
GO:0000166 |
nucleotide binding |
GO:0005215 |
transporter activity |
GO:0005515 |
protein binding |
GO:0005524 |
ATP binding |
GO:0005624 |
membrane fraction |
GO:0006810 |
transport |
GO:0008559 |
xenobiotic-transporting ATPase activity |
GO:0009986 |
cell surface |
GO:0016020 |
membrane |
GO:0016021 |
integral to membrane |
GO:0016324 |
apical plasma membrane |
GO:0016787 |
hydrolase activity |
GO:0016887 |
ATPase activity |
GO:0042493 |
response to drug |
GO:0042626 |
ATPase activity, coupled to transmembrane movement of substances |
GO:0046581 |
intercellular canaliculus |
GO:0055085 |
transmembrane transport |