Gene basic information
| LiverAtlas Gene ID |
HuLG003515 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SERPINA1 |
|
Synonyms |
A1A|A1AT|AAT|MGC23330|MGC9222|PI|PI1|PRO2275|alpha1AT |
|
Gene name |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
14 |
|
Genomics Location |
14q32.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
Liver fibrosis and liver cirrhosis Liver fibrosis and liver cirrhosis caused by hepatitis C infection |
|
Database cross reference |
HGNC:8941
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001666 |
response to hypoxia |
|
GO:0002020 |
protease binding |
|
GO:0002576 |
platelet degranulation |
|
GO:0004867 |
serine-type endopeptidase inhibitor activity |
|
GO:0005515 |
protein binding |
|
GO:0005576 |
extracellular region |
|
GO:0005578 |
proteinaceous extracellular matrix |
|
GO:0005615 |
extracellular space |
|
GO:0006953 |
acute-phase response |
|
GO:0006954 |
inflammatory response |
|
GO:0007596 |
blood coagulation |
|
GO:0010288 |
response to lead ion |
|
GO:0010951 |
negative regulation of endopeptidase activity |
|
GO:0014070 |
response to organic cyclic compound |
|
GO:0030162 |
regulation of proteolysis |
|
GO:0030168 |
platelet activation |
|
GO:0031093 |
platelet alpha granule lumen |
|
GO:0032355 |
response to estradiol stimulus |
|
GO:0032496 |
response to lipopolysaccharide |
|
GO:0033986 |
response to methanol |
|
GO:0034014 |
response to triglyceride |
|
GO:0034097 |
response to cytokine stimulus |
|
GO:0046687 |
response to chromate |
