Gene basic information
| LiverAtlas Gene ID |
HuLG003520 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SERPINE2 |
|
Synonyms |
DKFZp686A13110|GDN|PIN7|PI7|PNN1|PN1|PNI |
|
Gene name |
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
2 |
|
Genomics Location |
2q33-q35 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:8951
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004867 |
serine-type endopeptidase inhibitor activity |
|
GO:0005102 |
receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005539 |
glycosaminoglycan binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005829 |
cytosol |
|
GO:0007275 |
multicellular organismal development |
|
GO:0007399 |
nervous system development |
|
GO:0008201 |
heparin binding |
|
GO:0010757 |
negative regulation of plasminogen activation |
|
GO:0010951 |
negative regulation of endopeptidase activity |
|
GO:0010955 |
negative regulation of protein maturation by peptide bond cleavage |
|
GO:0030154 |
cell differentiation |
|
GO:0030195 |
negative regulation of blood coagulation |
|
GO:0030334 |
regulation of cell migration |
|
GO:0030414 |
peptidase inhibitor activity |
|
GO:0031012 |
extracellular matrix |
|
GO:0031091 |
platelet alpha granule |
|
GO:0031232 |
extrinsic to external side of plasma membrane |
|
GO:0031594 |
neuromuscular junction |
|
GO:0045861 |
negative regulation of proteolysis |
|
GO:0048711 |
positive regulation of astrocyte differentiation |
|
GO:0090331 |
negative regulation of platelet aggregation |
