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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003582

Entrez Gene ID

5340

Official Gene Symbol

PLG

Synonyms

DKFZp779M0222

Gene name

plasminogen

Gene Type

protein-coding

Chromosome

6

Genomics Location

6q26

Known cancer genes

Yes

Protein products

Plasminogen

HCG2029799, isoform CRA b

PLG protein

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Database cross reference

HGNC:9071
MIM:173350
Ensembl:ENSG00000122194
HPRD:01417
RefSeq Genomic nucleotide accession:AC_000049
RefSeq Genomic nucleotide gi:89161209

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002576

platelet degranulation

GO:0004252

serine-type endopeptidase activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0005886

plasma membrane

GO:0006508

proteolysis

GO:0007596

blood coagulation

GO:0008233

peptidase activity

GO:0008285

negative regulation of cell proliferation

GO:0010812

negative regulation of cell-substrate adhesion

GO:0022617

extracellular matrix disassembly

GO:0030168

platelet activation

GO:0031093

platelet alpha granule lumen

GO:0031232

extrinsic to external side of plasma membrane

GO:0034185

apolipoprotein binding

GO:0042730

fibrinolysis

GO:0043498

cell surface binding

GO:0048771

tissue remodeling

GO:0051918

negative regulation of fibrinolysis

GO:0051919

positive regulation of fibrinolysis