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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003603

Entrez Gene ID

5364

Official Gene Symbol

PLXNB1

Synonyms

KIAA0407|MGC149167|PLEXINNB1|PLXN5|SEP

Gene name

plexin B1

Gene Type

protein-coding

Chromosome

3

Genomics Location

3p21.31

Known cancer genes

Yes

Protein products

Plexin-B1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9103
MIM:601053
Ensembl:ENSG00000164050
HPRD:03032
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0002116

semaphorin receptor complex

GO:0004872

receptor activity

GO:0004888

transmembrane receptor activity

GO:0005096

GTPase activator activity

GO:0005515

protein binding

GO:0005576

extracellular region

GO:0005622

intracellular

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0007165

signal transduction

GO:0007275

multicellular organismal development

GO:0007411

axon guidance

GO:0008360

regulation of cell shape

GO:0016477

cell migration

GO:0017154

semaphorin receptor activity

GO:0030215

semaphorin receptor binding

GO:0035556

intracellular signal transduction

GO:0043547

positive regulation of GTPase activity

GO:0050772

positive regulation of axonogenesis

GO:0051056

regulation of small GTPase mediated signal transduction

GO:0051493

regulation of cytoskeleton organization

GO:0071526

semaphorin-plexin signaling pathway