Gene basic information
| LiverAtlas Gene ID |
HuLG003605 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PMAIP1 |
|
Synonyms |
APR|NOXA |
|
Gene name |
phorbol-12-myristate-13-acetate-induced protein 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
18 |
|
Genomics Location |
18q21.32 |
|
Protein products |
|
|
Database cross reference |
HGNC:9108
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001844 |
protein insertion into mitochondrial membrane involved in induction of apoptosis |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005739 |
mitochondrion |
|
GO:0005741 |
mitochondrial outer membrane |
|
GO:0005829 |
cytosol |
|
GO:0006915 |
apoptosis |
|
GO:0006917 |
induction of apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0006921 |
cellular component disassembly involved in apoptosis |
|
GO:0006926 |
virus-infected cell apoptosis |
|
GO:0006974 |
response to DNA damage stimulus |
|
GO:0008629 |
induction of apoptosis by intracellular signals |
|
GO:0008633 |
activation of pro-apoptotic gene products |
|
GO:0009411 |
response to UV |
|
GO:0010165 |
response to X-ray |
|
GO:0010498 |
proteasomal protein catabolic process |
|
GO:0010907 |
positive regulation of glucose metabolic process |
|
GO:0010917 |
negative regulation of mitochondrial membrane potential |
|
GO:0032461 |
positive regulation of protein oligomerization |
|
GO:0042149 |
cellular response to glucose starvation |
|
GO:0043029 |
T cell homeostasis |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043280 |
positive regulation of caspase activity |
|
GO:0043331 |
response to dsRNA |
|
GO:0043517 |
positive regulation of DNA damage response, signal transduction by p53 class mediator |
|
GO:0043525 |
positive regulation of neuron apoptosis |
|
GO:0046902 |
regulation of mitochondrial membrane permeability |
|
GO:0048147 |
negative regulation of fibroblast proliferation |
|
GO:0071456 |
cellular response to hypoxia |
|
GO:0072332 |
signal transduction by p53 class mediator resulting in induction of apoptosis |
|
GO:0072593 |
reactive oxygen species metabolic process |
|
GO:0090200 |
positive regulation of release of cytochrome c from mitochondria |
