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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003633

Entrez Gene ID

5424

Official Gene Symbol

POLD1

Synonyms

CDC2|POLD

Gene name

polymerase (DNA directed), delta 1, catalytic subunit 125kDa

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q13.3

Known cancer genes

Yes

Protein products

DNA polymerase delta catalytic subunit

DNA polymerase

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9175
MIM:174761
Ensembl:ENSG00000062822
HPRD:08882
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000084

S phase of mitotic cell cycle

GO:0000109

nucleotide-excision repair complex

GO:0000166

nucleotide binding

GO:0000278

mitotic cell cycle

GO:0000722

telomere maintenance via recombination

GO:0000723

telomere maintenance

GO:0000731

DNA synthesis involved in DNA repair

GO:0003677

DNA binding

GO:0003682

chromatin binding

GO:0003887

DNA-directed DNA polymerase activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0006139

nucleobase, nucleoside, nucleotide and nucleic acid metabolic process

GO:0006260

DNA replication

GO:0006271

DNA strand elongation involved in DNA replication

GO:0006281

DNA repair

GO:0006283

transcription-coupled nucleotide-excision repair

GO:0006284

base-excision repair

GO:0006287

base-excision repair, gap-filling

GO:0006289

nucleotide-excision repair

GO:0006297

nucleotide-excision repair, DNA gap filling

GO:0007346

regulation of mitotic cell cycle

GO:0008296

3'-5'-exodeoxyribonuclease activity

GO:0009411

response to UV

GO:0016740

transferase activity

GO:0016779

nucleotidyltransferase activity

GO:0016787

hydrolase activity

GO:0032201

telomere maintenance via semi-conservative replication

GO:0043137

DNA replication, removal of RNA primer

GO:0043625

delta DNA polymerase complex

GO:0045004

DNA replication proofreading

GO:0046872

metal ion binding