Gene basic information
| LiverAtlas Gene ID |
HuLG003673 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PPARG |
|
Synonyms |
CIMT1|GLM1|NR1C3|PPARG1|PPARG2|PPARgamma |
|
Gene name |
peroxisome proliferator-activated receptor gamma |
|
Gene Type |
protein-coding |
|
Chromosome |
3 |
|
Genomics Location |
3p25 |
|
Known cancer genes |
Yes |
|
Protein products |
Peroxisome proliferator activated receptor gamma Peroxisome proliferative activated receptor gamma isoform 6 variant |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9236
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0001818 |
negative regulation of cytokine production |
|
GO:0001890 |
placenta development |
|
GO:0002674 |
negative regulation of acute inflammatory response |
|
GO:0003677 |
DNA binding |
|
GO:0003682 |
chromatin binding |
|
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
|
GO:0003707 |
steroid hormone receptor activity |
|
GO:0004879 |
ligand-dependent nuclear receptor activity |
|
GO:0004955 |
prostaglandin receptor activity |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006351 |
transcription, DNA-dependent |
|
GO:0006629 |
lipid metabolic process |
|
GO:0006917 |
induction of apoptosis |
|
GO:0006919 |
activation of caspase activity |
|
GO:0007165 |
signal transduction |
|
GO:0007507 |
heart development |
|
GO:0007584 |
response to nutrient |
|
GO:0008144 |
drug binding |
|
GO:0008217 |
regulation of blood pressure |
|
GO:0008270 |
zinc ion binding |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0009409 |
response to cold |
|
GO:0010467 |
gene expression |
|
GO:0010745 |
negative regulation of macrophage derived foam cell differentiation |
|
GO:0010871 |
negative regulation of receptor biosynthetic process |
|
GO:0010887 |
negative regulation of cholesterol storage |
|
GO:0010891 |
negative regulation of sequestering of triglyceride |
|
GO:0015909 |
long-chain fatty acid transport |
|
GO:0019216 |
regulation of lipid metabolic process |
|
GO:0019899 |
enzyme binding |
|
GO:0030224 |
monocyte differentiation |
|
GO:0030308 |
negative regulation of cell growth |
|
GO:0030855 |
epithelial cell differentiation |
|
GO:0031000 |
response to caffeine |
|
GO:0031100 |
organ regeneration |
|
GO:0032869 |
cellular response to insulin stimulus |
|
GO:0033189 |
response to vitamin A |
|
GO:0033613 |
activating transcription factor binding |
|
GO:0033993 |
response to lipid |
|
GO:0034339 |
regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor |
|
GO:0042493 |
response to drug |
|
GO:0042593 |
glucose homeostasis |
|
GO:0042953 |
lipoprotein transport |
|
GO:0043565 |
sequence-specific DNA binding |
|
GO:0043627 |
response to estrogen stimulus |
|
GO:0045087 |
innate immune response |
|
GO:0045165 |
cell fate commitment |
|
GO:0045600 |
positive regulation of fat cell differentiation |
|
GO:0045713 |
low-density lipoprotein particle receptor biosynthetic process |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046321 |
positive regulation of fatty acid oxidation |
|
GO:0046872 |
metal ion binding |
|
GO:0046965 |
retinoid X receptor binding |
|
GO:0048469 |
cell maturation |
|
GO:0048714 |
positive regulation of oligodendrocyte differentiation |
|
GO:0050544 |
arachidonic acid binding |
|
GO:0050872 |
white fat cell differentiation |
|
GO:0050873 |
brown fat cell differentiation |
|
GO:0051091 |
positive regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0051974 |
negative regulation of telomerase activity |
|
GO:0055088 |
lipid homeostasis |
|
GO:0055098 |
response to low-density lipoprotein particle stimulus |
|
GO:0060336 |
negative regulation of interferon-gamma-mediated signaling pathway |
|
GO:0071285 |
cellular response to lithium ion |
|
GO:0071407 |
cellular response to organic cyclic compound |
