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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003676

Entrez Gene ID

5471

Official Gene Symbol

PPAT

Synonyms

ATASE|GPAT|PRAT

Gene name

phosphoribosyl pyrophosphate amidotransferase

Gene Type

protein-coding

Chromosome

4

Genomics Location

4q12

Protein products

Amidophosphoribosyltransferase

Amidophosphoribosyltransferase

Phosphoribosyl pyrophosphate amidotransferase proprotein variant

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9238
MIM:172450
Ensembl:ENSG00000128059
HPRD:01402
RefSeq Genomic nucleotide accession:AC_000047
RefSeq Genomic nucleotide gi:89161206

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004044

amidophosphoribosyltransferase activity

GO:0005625

soluble fraction

GO:0005829

cytosol

GO:0006144

purine base metabolic process

GO:0006164

purine nucleotide biosynthetic process

GO:0006541

glutamine metabolic process

GO:0007595

lactation

GO:0009113

purine base biosynthetic process

GO:0009116

nucleoside metabolic process

GO:0009168

purine ribonucleoside monophosphate biosynthetic process

GO:0016757

transferase activity, transferring glycosyl groups

GO:0031100

organ regeneration

GO:0032869

cellular response to insulin stimulus

GO:0046872

metal ion binding

GO:0051289

protein homotetramerization

GO:0051539

4 iron, 4 sulfur cluster binding

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process

GO:0060135

maternal process involved in female pregnancy