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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003679

Entrez Gene ID

5476

Official Gene Symbol

CTSA

Synonyms

GLB2|GSL|NGBE|PPCA|PPGB

Gene name

cathepsin A

Gene Type

protein-coding

Chromosome

20

Genomics Location

20q13.1

Known cancer genes

Yes

Protein products

cDNA FLJ60397, highly similar to Lysosomal protective protein (EC 3.4.16.5)

Lysosomal protective protein

Carrier family 6, member 8 variant

Cathepsin A

Cathepsin A

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9251
MIM:613111
Ensembl:ENSG00000064601
HPRD:02020
RefSeq Genomic nucleotide accession:AC_000063
RefSeq Genomic nucleotide gi:89161200

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004180

carboxypeptidase activity

GO:0004185

serine-type carboxypeptidase activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005739

mitochondrion

GO:0005764

lysosome

GO:0005783

endoplasmic reticulum

GO:0006508

proteolysis

GO:0006886

intracellular protein transport

GO:0008047

enzyme activator activity

GO:0008233

peptidase activity

GO:0043085

positive regulation of catalytic activity

GO:0043231

intracellular membrane-bounded organelle