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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003688

Entrez Gene ID

5498

Official Gene Symbol

PPOX

Synonyms

MGC8485|PPO|V290M|VP

Gene name

protoporphyrinogen oxidase

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q22

Known cancer genes

Yes

Protein products

Protoporphyrinogen oxidase, isoform CRA d

Protoporphyrinogen oxidase

Protoporphyrinogen oxidase

Related liver disease name

Hepatocellular carcinoma

Variegate porphyria

Database cross reference

HGNC:9280
MIM:600923
Ensembl:ENSG00000143224
HPRD:02953
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004729

oxygen-dependent protoporphyrinogen oxidase activity

GO:0005488

binding

GO:0005739

mitochondrion

GO:0005758

mitochondrial intermembrane space

GO:0006778

porphyrin metabolic process

GO:0006779

porphyrin biosynthetic process

GO:0006783

heme biosynthetic process

GO:0016020

membrane

GO:0016491

oxidoreductase activity

GO:0031304

intrinsic to mitochondrial inner membrane

GO:0031966

mitochondrial membrane

GO:0050660

flavin adenine dinucleotide binding

GO:0055114

oxidation-reduction process