Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003701

Entrez Gene ID

5516

Official Gene Symbol

PPP2CB

Synonyms

PP2Abeta|PP2CB

Gene name

protein phosphatase 2, catalytic subunit, beta isozyme

Gene Type

protein-coding

Chromosome

8

Genomics Location

8p12

Known cancer genes

Yes

Protein products

Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9300
MIM:176916
Ensembl:ENSG00000104695
HPRD:01487
RefSeq Genomic nucleotide accession:AC_000051
RefSeq Genomic nucleotide gi:89161214

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000159

protein phosphatase type 2A complex

GO:0000775

chromosome, centromeric region

GO:0000922

spindle pole

GO:0004722

protein serine/threonine phosphatase activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005694

chromosome

GO:0005737

cytoplasm

GO:0005856

cytoskeleton

GO:0006470

protein dephosphorylation

GO:0008022

protein C-terminus binding

GO:0010468

regulation of gene expression

GO:0016787

hydrolase activity

GO:0042542

response to hydrogen peroxide

GO:0043066

negative regulation of apoptosis

GO:0043161

proteasomal ubiquitin-dependent protein catabolic process

GO:0046580

negative regulation of Ras protein signal transduction

GO:0046677

response to antibiotic

GO:0046872

metal ion binding