Gene basic information
| LiverAtlas Gene ID |
HuLG003714 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PPP3CA |
|
Synonyms |
CALN|CALNA|CALNA1|CCN1|CNA1|PPP2B |
|
Gene name |
protein phosphatase 3, catalytic subunit, alpha isozyme |
|
Gene Type |
protein-coding |
|
Chromosome |
4 |
|
Genomics Location |
4q24 |
|
Known cancer genes |
Yes |
|
Protein products |
Serine/threonine-protein phosphatase Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9314
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0001975 |
response to amphetamine |
|
GO:0004722 |
protein serine/threonine phosphatase activity |
|
GO:0004723 |
calcium-dependent protein serine/threonine phosphatase activity |
|
GO:0005509 |
calcium ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005516 |
calmodulin binding |
|
GO:0005625 |
soluble fraction |
|
GO:0005626 |
insoluble fraction |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005792 |
microsome |
|
GO:0005829 |
cytosol |
|
GO:0005955 |
calcineurin complex |
|
GO:0006470 |
protein dephosphorylation |
|
GO:0006606 |
protein import into nucleus |
|
GO:0006816 |
calcium ion transport |
|
GO:0006950 |
response to stress |
|
GO:0016020 |
membrane |
|
GO:0016787 |
hydrolase activity |
|
GO:0030018 |
Z disc |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0046676 |
negative regulation of insulin secretion |
|
GO:0046982 |
protein heterodimerization activity |
|
GO:0048741 |
skeletal muscle fiber development |
|
GO:0050804 |
regulation of synaptic transmission |
|
GO:0060079 |
regulation of excitatory postsynaptic membrane potential |
|
GO:0071333 |
cellular response to glucose stimulus |
