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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003747

Entrez Gene ID

5573

Official Gene Symbol

PRKAR1A

Synonyms

CAR|CNC|CNC1|DKFZp779L0468|MGC17251|PKR1|PPNAD1|PRKAR1|TSE1

Gene name

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q23-q24

Known cancer genes

Yes

Protein products

Protein kinase, cAMP-dependent, regulatory, type I, alpha (Tissue specific extinguisher 1), isoform CRA a

cAMP-dependent protein kinase type I-alpha regulatory subunit

Putative uncharacterized protein DKFZp779L0468

Protein kinase A type 1a regulatory subunit

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9388
MIM:188830
Ensembl:ENSG00000108946
HPRD:01786
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0001707

mesoderm formation

GO:0001932

regulation of protein phosphorylation

GO:0005515

protein binding

GO:0005829

cytosol

GO:0005952

cAMP-dependent protein kinase complex

GO:0006112

energy reserve metabolic process

GO:0006357

regulation of transcription from RNA polymerase II promoter

GO:0006833

water transport

GO:0007202

activation of phospholipase C activity

GO:0007596

blood coagulation

GO:0008603

cAMP-dependent protein kinase regulator activity

GO:0030552

cAMP binding

GO:0031594

neuromuscular junction

GO:0034199

activation of protein kinase A activity

GO:0035556

intracellular signal transduction

GO:0043234

protein complex

GO:0048011

nerve growth factor receptor signaling pathway

GO:0050796

regulation of insulin secretion

GO:0055085

transmembrane transport

GO:0071377

cellular response to glucagon stimulus