Gene basic information
| LiverAtlas Gene ID |
HuLG003751 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PRKCA |
|
Synonyms |
AAG6|MGC129900|MGC129901|PKCNalpha|PKCA|PRKACA |
|
Gene name |
protein kinase C, alpha |
|
Gene Type |
protein-coding |
|
Chromosome |
17 |
|
Genomics Location |
17q22-q23.2 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9393
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004697 |
protein kinase C activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005624 |
membrane fraction |
|
GO:0005654 |
nucleoplasm |
|
GO:0005737 |
cytoplasm |
|
GO:0005783 |
endoplasmic reticulum |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006112 |
energy reserve metabolic process |
|
GO:0006468 |
protein phosphorylation |
|
GO:0007202 |
activation of phospholipase C activity |
|
GO:0007268 |
synaptic transmission |
|
GO:0007596 |
blood coagulation |
|
GO:0008270 |
zinc ion binding |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0016070 |
RNA metabolic process |
|
GO:0016071 |
mRNA metabolic process |
|
GO:0019899 |
enzyme binding |
|
GO:0030168 |
platelet activation |
|
GO:0035403 |
histone kinase activity (H3-T6 specific) |
|
GO:0035408 |
histone H3-T6 phosphorylation |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0043536 |
positive regulation of blood vessel endothelial cell migration |
|
GO:0046872 |
metal ion binding |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0050796 |
regulation of insulin secretion |
|
GO:0070555 |
response to interleukin-1 |
