Gene basic information
| LiverAtlas Gene ID |
HuLG003764 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PRKDC |
|
Synonyms |
DNANPKcs|DNAPK|DNPK1|HYRC|HYRC1|XRCC7|p350 |
|
Gene name |
protein kinase, DNA-activated, catalytic polypeptide |
|
Gene Type |
protein-coding |
|
Chromosome |
8 |
|
Genomics Location |
8q11 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9413
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0000723 |
telomere maintenance |
|
GO:0001756 |
somitogenesis |
|
GO:0002326 |
B cell lineage commitment |
|
GO:0002328 |
pro-B cell differentiation |
|
GO:0002360 |
T cell lineage commitment |
|
GO:0003677 |
DNA binding |
|
GO:0004672 |
protein kinase activity |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004677 |
DNA-dependent protein kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005667 |
transcription factor complex |
|
GO:0005958 |
DNA-dependent protein kinase-DNA ligase 4 complex |
|
GO:0006281 |
DNA repair |
|
GO:0006302 |
double-strand break repair |
|
GO:0006303 |
double-strand break repair via nonhomologous end joining |
|
GO:0006310 |
DNA recombination |
|
GO:0006464 |
protein modification process |
|
GO:0007420 |
brain development |
|
GO:0007507 |
heart development |
|
GO:0008134 |
transcription factor binding |
|
GO:0010332 |
response to gamma radiation |
|
GO:0016301 |
kinase activity |
|
GO:0016310 |
phosphorylation |
|
GO:0018105 |
peptidyl-serine phosphorylation |
|
GO:0019899 |
enzyme binding |
|
GO:0030098 |
lymphocyte differentiation |
|
GO:0031648 |
protein destabilization |
|
GO:0032869 |
cellular response to insulin stimulus |
|
GO:0033077 |
T cell differentiation in thymus |
|
GO:0033152 |
immunoglobulin V(D)J recombination |
|
GO:0033153 |
T cell receptor V(D)J recombination |
|
GO:0035234 |
germ cell programmed cell death |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0070419 |
nonhomologous end joining complex |
