Gene basic information
| LiverAtlas Gene ID |
HuLG003768 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
MAPK3 |
|
Synonyms |
ERK1|HS44KDAP|HUMKER1A|MGC20180|P44ERK1|P44MAPK|PRKM3 |
|
Gene name |
mitogen-activated protein kinase 3 |
|
Gene Type |
protein-coding |
|
Chromosome |
16 |
|
Genomics Location |
16p11.2 |
|
Known cancer genes |
Yes |
|
Protein products |
Extracellular signal-regulated kinase-1 splice variant Mitogen-activated protein kinase 3 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:6877
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000165 |
MAPKKK cascade |
|
GO:0000166 |
nucleotide binding |
|
GO:0000186 |
activation of MAPKK activity |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0001784 |
phosphotyrosine binding |
|
GO:0002224 |
toll-like receptor signaling pathway |
|
GO:0002755 |
MyD88-dependent toll-like receptor signaling pathway |
|
GO:0002756 |
MyD88-independent toll-like receptor signaling pathway |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0004707 |
MAP kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005654 |
nucleoplasm |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0006360 |
transcription from RNA polymerase I promoter |
|
GO:0006361 |
transcription initiation from RNA polymerase I promoter |
|
GO:0006468 |
protein phosphorylation |
|
GO:0006974 |
response to DNA damage stimulus |
|
GO:0007049 |
cell cycle |
|
GO:0007173 |
epidermal growth factor receptor signaling pathway |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0007265 |
Ras protein signal transduction |
|
GO:0007411 |
axon guidance |
|
GO:0007596 |
blood coagulation |
|
GO:0008063 |
Toll signaling pathway |
|
GO:0008286 |
insulin receptor signaling pathway |
|
GO:0009887 |
organ morphogenesis |
|
GO:0016301 |
kinase activity |
|
GO:0016310 |
phosphorylation |
|
GO:0019233 |
sensory perception of pain |
|
GO:0019902 |
phosphatase binding |
|
GO:0030168 |
platelet activation |
|
GO:0031663 |
lipopolysaccharide-mediated signaling pathway |
|
GO:0032496 |
response to lipopolysaccharide |
|
GO:0033129 |
positive regulation of histone phosphorylation |
|
GO:0034130 |
toll-like receptor 1 signaling pathway |
|
GO:0034134 |
toll-like receptor 2 signaling pathway |
|
GO:0034138 |
toll-like receptor 3 signaling pathway |
|
GO:0034142 |
toll-like receptor 4 signaling pathway |
|
GO:0035066 |
positive regulation of histone acetylation |
|
GO:0043330 |
response to exogenous dsRNA |
|
GO:0044419 |
interspecies interaction between organisms |
|
GO:0045087 |
innate immune response |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0051090 |
regulation of sequence-specific DNA binding transcription factor activity |
|
GO:0051216 |
cartilage development |
|
GO:0051403 |
stress-activated MAPK cascade |
|
GO:0070498 |
interleukin-1-mediated signaling pathway |
|
GO:0071260 |
cellular response to mechanical stimulus |
