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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003796

Entrez Gene ID

5627

Official Gene Symbol

PROS1

Synonyms

PROS|PS21|PS22|PS23|PS24|PS25|PSA

Gene name

protein S (alpha)

Gene Type

protein-coding

Chromosome

3

Genomics Location

3q11.2

Known cancer genes

Yes

Protein products

Vitamin K-dependent protein S

Protein S

Related liver disease name

Liver fibrosis and liver cirrhosis

Hepatocellular carcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:9456
MIM:176880
Ensembl:ENSG00000184500
HPRD:01473
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000139

Golgi membrane

GO:0002576

platelet degranulation

GO:0004866

endopeptidase inhibitor activity

GO:0005509

calcium ion binding

GO:0005576

extracellular region

GO:0005789

endoplasmic reticulum membrane

GO:0005796

Golgi lumen

GO:0006508

proteolysis

GO:0007596

blood coagulation

GO:0010951

negative regulation of endopeptidase activity

GO:0017187

peptidyl-glutamic acid carboxylation

GO:0030168

platelet activation

GO:0031093

platelet alpha granule lumen

GO:0043687

post-translational protein modification

GO:0044267

cellular protein metabolic process

GO:0050900

leukocyte migration