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Gene basic information

LiverAtlas Gene ID

HuLG003851

Entrez Gene ID

5701

Official Gene Symbol

PSMC2

Synonyms

MGC3004|MSS1|Nbla10058|S7

Gene name

proteasome (prosome, macropain) 26S subunit, ATPase, 2

Gene Type

protein-coding

Chromosome

7

Genomics Location

7q22.1-q22.3

Known cancer genes

Yes

Protein products

cDNA FLJ52010, highly similar to 26S protease regulatory subunit 7

26S protease regulatory subunit 7

Putative uncharacterized protein PSMC2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9548
MIM:154365
Ensembl:ENSG00000161057
HPRD:01105
RefSeq Genomic nucleotide accession:AC_000050
RefSeq Genomic nucleotide gi:89161211

 

Ontology annotation

GO ID

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000082

G1/S transition of mitotic cell cycle

GO:0000084

S phase of mitotic cell cycle

GO:0000166

nucleotide binding

GO:0000216

M/G1 transition of mitotic cell cycle

GO:0000278

mitotic cell cycle

GO:0000502

proteasome complex

GO:0005515

protein binding

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0005739

mitochondrion

GO:0006200

ATP catabolic process

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0006521

regulation of cellular amino acid metabolic process

GO:0006915

apoptosis

GO:0006977

DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest

GO:0016032

viral reproduction

GO:0016070

RNA metabolic process

GO:0016071

mRNA metabolic process

GO:0016787

hydrolase activity

GO:0016887

ATPase activity

GO:0030163

protein catabolic process

GO:0031145

anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process

GO:0034641

cellular nitrogen compound metabolic process

GO:0042981

regulation of apoptosis

GO:0044419

interspecies interaction between organisms

GO:0051436

negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051437

positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle

GO:0051439

regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle