Gene basic information
| LiverAtlas Gene ID |
HuLG003853 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PSMC4 |
|
Synonyms |
MGC13687|MGC23214|MGC8570|MIP224|S6|TBP7 |
|
Gene name |
proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
|
Gene Type |
protein-coding |
|
Chromosome |
19 |
|
Genomics Location |
19q13.11-q13.13 |
|
Known cancer genes |
Yes |
|
Protein products |
Proteasome (Prosome, macropain) 26S subunit, ATPase, 4, isoform CRA b |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9551
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000075 |
cell cycle checkpoint |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0000084 |
S phase of mitotic cell cycle |
|
GO:0000166 |
nucleotide binding |
|
GO:0000216 |
M/G1 transition of mitotic cell cycle |
|
GO:0000278 |
mitotic cell cycle |
|
GO:0000502 |
proteasome complex |
|
GO:0001824 |
blastocyst development |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005634 |
nucleus |
|
GO:0005730 |
nucleolus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0006200 |
ATP catabolic process |
|
GO:0006508 |
proteolysis |
|
GO:0006521 |
regulation of cellular amino acid metabolic process |
|
GO:0006915 |
apoptosis |
|
GO:0006977 |
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest |
|
GO:0016032 |
viral reproduction |
|
GO:0016070 |
RNA metabolic process |
|
GO:0016071 |
mRNA metabolic process |
|
GO:0016787 |
hydrolase activity |
|
GO:0016887 |
ATPase activity |
|
GO:0030163 |
protein catabolic process |
|
GO:0031145 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
GO:0034641 |
cellular nitrogen compound metabolic process |
|
GO:0042981 |
regulation of apoptosis |
|
GO:0051436 |
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0051437 |
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0051439 |
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
