Gene basic information
| LiverAtlas Gene ID |
HuLG003864 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PSMD10 |
|
Synonyms |
dJ889N15.2|p28|p28(GANK) |
|
Gene name |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 |
|
Gene Type |
protein-coding |
|
Chromosome |
0 |
|
Genomics Location |
Xq22.3 |
|
Known cancer genes |
Yes |
|
Protein products |
Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10 Proteasome (Prosome, macropain) 26S subunit, non-ATPase, 10 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9555
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000075 |
cell cycle checkpoint |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0000084 |
S phase of mitotic cell cycle |
|
GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
|
GO:0000216 |
M/G1 transition of mitotic cell cycle |
|
GO:0000278 |
mitotic cell cycle |
|
GO:0000502 |
proteasome complex |
|
GO:0005515 |
protein binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005838 |
proteasome regulatory particle |
|
GO:0006521 |
regulation of cellular amino acid metabolic process |
|
GO:0006915 |
apoptosis |
|
GO:0006977 |
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest |
|
GO:0007253 |
cytoplasmic sequestering of NF-kappaB |
|
GO:0008134 |
transcription factor binding |
|
GO:0008540 |
proteasome regulatory particle, base subcomplex |
|
GO:0015629 |
actin cytoskeleton |
|
GO:0016032 |
viral reproduction |
|
GO:0016070 |
RNA metabolic process |
|
GO:0016071 |
mRNA metabolic process |
|
GO:0030307 |
positive regulation of cell growth |
|
GO:0031145 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
GO:0031398 |
positive regulation of protein ubiquitination |
|
GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
|
GO:0032436 |
positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
|
GO:0034641 |
cellular nitrogen compound metabolic process |
|
GO:0042981 |
regulation of apoptosis |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043409 |
negative regulation of MAPKKK cascade |
|
GO:0043518 |
negative regulation of DNA damage response, signal transduction by p53 class mediator |
|
GO:0045111 |
intermediate filament cytoskeleton |
|
GO:0045737 |
positive regulation of cyclin-dependent protein kinase activity |
|
GO:0051436 |
negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0051437 |
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0051439 |
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle |
|
GO:0070682 |
proteasome regulatory particle assembly |
|
GO:0090201 |
negative regulation of release of cytochrome c from mitochondria |
