Gene basic information
| LiverAtlas Gene ID |
HuLG003907 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
PTPN11 |
|
Synonyms |
BPTP3|CFC|MGC14433|NS1|PTPN1D|PTP2C|SHNPTP2|SHNPTP3|SHP2 |
|
Gene name |
protein tyrosine phosphatase, non-receptor type 11 |
|
Gene Type |
protein-coding |
|
Chromosome |
12 |
|
Genomics Location |
12q24 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9644
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0004725 |
protein tyrosine phosphatase activity |
|
GO:0004726 |
non-membrane spanning protein tyrosine phosphatase activity |
|
GO:0005515 |
protein binding |
|
GO:0005737 |
cytoplasm |
|
GO:0005829 |
cytosol |
|
GO:0007173 |
epidermal growth factor receptor signaling pathway |
|
GO:0007411 |
axon guidance |
|
GO:0007596 |
blood coagulation |
|
GO:0008286 |
insulin receptor signaling pathway |
|
GO:0008543 |
fibroblast growth factor receptor signaling pathway |
|
GO:0016787 |
hydrolase activity |
|
GO:0019221 |
cytokine-mediated signaling pathway |
|
GO:0030168 |
platelet activation |
|
GO:0031295 |
T cell costimulation |
|
GO:0033628 |
regulation of cell adhesion mediated by integrin |
|
GO:0034329 |
cell junction assembly |
|
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
|
GO:0048013 |
ephrin receptor signaling pathway |
|
GO:0050900 |
leukocyte migration |
|
GO:0060333 |
interferon-gamma-mediated signaling pathway |
|
GO:0060334 |
regulation of interferon-gamma-mediated signaling pathway |
|
GO:0060337 |
type I interferon-mediated signaling pathway |
|
GO:0060338 |
regulation of type I interferon-mediated signaling pathway |
