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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003912

Entrez Gene ID

5787

Official Gene Symbol

PTPRB

Synonyms

DKFZp686E2262|DKFZp686H15164|FLJ44133|HPTPNBETA|HPTPB|MGC142023|MGC59935|PTPB|RNPTPNBETA|VEPTP

Gene name

protein tyrosine phosphatase, receptor type, B

Gene Type

protein-coding

Chromosome

12

Genomics Location

12q15-q21

Known cancer genes

Yes

Protein products

Receptor-type tyrosine-protein phosphatase beta

cDNA FLJ44133 fis, clone THYMU2008725, highly similar to PROTEIN-TYROSINE PHOSPHATASE BETA (EC 3.1.3.48)

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9665
MIM:176882
Ensembl:ENSG00000127329
HPRD:01474
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001525

angiogenesis

GO:0005001

transmembrane receptor protein tyrosine phosphatase activity

GO:0005515

protein binding

GO:0005887

integral to plasma membrane

GO:0006470

protein dephosphorylation

GO:0006796

phosphate metabolic process

GO:0016020

membrane

GO:0016311

dephosphorylation

GO:0016787

hydrolase activity