Gene basic information
LiverAtlas Gene ID |
HuLG003913 |
Entrez Gene ID |
|
Official Gene Symbol |
PTPRC |
Synonyms |
B220|CD45|CD45R|GP180|LNCA|LCA|LY5|T200 |
Gene name |
protein tyrosine phosphatase, receptor type, C |
Gene Type |
protein-coding |
Chromosome |
1 |
Genomics Location |
1q31-q32 |
Known cancer genes |
Yes |
Protein products |
Protein tyrosine phosphatase, receptor type, C Protein tyrosine phosphatase, receptor type, C Receptor-type tyrosine-protein phosphatase C Protein tyrosine phosphatase, receptor type, C |
Related liver disease name |
|
Database cross reference |
HGNC:9666
|
Liver relevance
HCC significant genes |
Yes/No |
Yes |
Evidence |
EHCO HCC.net |
|
Quality score |
|
Ontology annotation
GO ID |
GO annotation |
GO:0001915 |
negative regulation of T cell mediated cytotoxicity |
GO:0001960 |
negative regulation of cytokine-mediated signaling pathway |
GO:0002378 |
immunoglobulin biosynthetic process |
GO:0004725 |
protein tyrosine phosphatase activity |
GO:0005001 |
transmembrane receptor protein tyrosine phosphatase activity |
GO:0005515 |
protein binding |
GO:0005886 |
plasma membrane |
GO:0005887 |
integral to plasma membrane |
GO:0005925 |
focal adhesion |
GO:0006469 |
negative regulation of protein kinase activity |
GO:0006470 |
protein dephosphorylation |
GO:0007166 |
cell surface receptor linked signaling pathway |
GO:0007411 |
axon guidance |
GO:0016311 |
dephosphorylation |
GO:0016787 |
hydrolase activity |
GO:0019901 |
protein kinase binding |
GO:0030217 |
T cell differentiation |
GO:0030890 |
positive regulation of B cell proliferation |
GO:0033261 |
regulation of S phase |
GO:0035335 |
peptidyl-tyrosine dephosphorylation |
GO:0042100 |
B cell proliferation |
GO:0042102 |
positive regulation of T cell proliferation |
GO:0045121 |
membrane raft |
GO:0045860 |
positive regulation of protein kinase activity |
GO:0050852 |
T cell receptor signaling pathway |
GO:0050853 |
B cell receptor signaling pathway |
GO:0050857 |
positive regulation of antigen receptor-mediated signaling pathway |
GO:0051209 |
release of sequestered calcium ion into cytosol |
GO:0051607 |
defense response to virus |
GO:0051726 |
regulation of cell cycle |