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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003913

Entrez Gene ID

5788

Official Gene Symbol

PTPRC

Synonyms

B220|CD45|CD45R|GP180|LNCA|LCA|LY5|T200

Gene name

protein tyrosine phosphatase, receptor type, C

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q31-q32

Known cancer genes

Yes

Protein products

Protein tyrosine phosphatase, receptor type, C

Protein tyrosine phosphatase, receptor type, C

Uncharacterized protein

Uncharacterized protein

Receptor-type tyrosine-protein phosphatase C

Protein tyrosine phosphatase, receptor type, C

Protein tyrosine phosphatase, receptor type, C

PTPRC protein

Related liver disease name

Hepatitis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Autoimmune hepatitis

Hepatocellular carcinoma

Primary biliary cirrhosis

Database cross reference

HGNC:9666
MIM:151460
Ensembl:ENSG00000081237
HPRD:01050
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001915

negative regulation of T cell mediated cytotoxicity

GO:0001960

negative regulation of cytokine-mediated signaling pathway

GO:0002378

immunoglobulin biosynthetic process

GO:0004725

protein tyrosine phosphatase activity

GO:0005001

transmembrane receptor protein tyrosine phosphatase activity

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0005925

focal adhesion

GO:0006469

negative regulation of protein kinase activity

GO:0006470

protein dephosphorylation

GO:0007166

cell surface receptor linked signaling pathway

GO:0007411

axon guidance

GO:0016311

dephosphorylation

GO:0016787

hydrolase activity

GO:0019901

protein kinase binding

GO:0030217

T cell differentiation

GO:0030890

positive regulation of B cell proliferation

GO:0033261

regulation of S phase

GO:0035335

peptidyl-tyrosine dephosphorylation

GO:0042100

B cell proliferation

GO:0042102

positive regulation of T cell proliferation

GO:0045121

membrane raft

GO:0045860

positive regulation of protein kinase activity

GO:0050852

T cell receptor signaling pathway

GO:0050853

B cell receptor signaling pathway

GO:0050857

positive regulation of antigen receptor-mediated signaling pathway

GO:0051209

release of sequestered calcium ion into cytosol

GO:0051607

defense response to virus

GO:0051726

regulation of cell cycle