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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003937

Entrez Gene ID

5819

Official Gene Symbol

PVRL2

Synonyms

CD112|HVEB|PRR2|PVRR2

Gene name

poliovirus receptor-related 2 (herpesvirus entry mediator B)

Gene Type

protein-coding

Chromosome

19

Genomics Location

19q13.2

Protein products

Poliovirus receptor-related protein 2

Poliovirus receptor related 2

Poliovirus receptor related 2

Poliovirus receptor related 2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9707
MIM:600798
Ensembl:ENSG00000130202
HPRD:02879
RefSeq Genomic nucleotide accession:AC_000062
RefSeq Genomic nucleotide gi:89161197

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0001675

acrosome assembly

GO:0002860

positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target

GO:0002891

positive regulation of immunoglobulin mediated immune response

GO:0005515

protein binding

GO:0005886

plasma membrane

GO:0005911

cell-cell junction

GO:0005915

zonula adherens

GO:0007010

cytoskeleton organization

GO:0007155

cell adhesion

GO:0007156

homophilic cell adhesion

GO:0007286

spermatid development

GO:0007289

spermatid nucleus differentiation

GO:0009566

fertilization

GO:0009986

cell surface

GO:0015026

coreceptor activity

GO:0016021

integral to membrane

GO:0019064

viral envelope fusion with host membrane

GO:0030382

sperm mitochondrion organization

GO:0032990

cell part morphogenesis

GO:0033005

positive regulation of mast cell activation

GO:0034329

cell junction assembly

GO:0034332

adherens junction organization

GO:0042271

susceptibility to natural killer cell mediated cytotoxicity

GO:0042803

protein homodimerization activity

GO:0043064

flagellum organization

GO:0044419

interspecies interaction between organisms

GO:0045216

cell-cell junction organization

GO:0045954

positive regulation of natural killer cell mediated cytotoxicity

GO:0046814

virion attachment, binding of host cell surface coreceptor

GO:0050776

regulation of immune response

GO:0050839

cell adhesion molecule binding

GO:0051654

establishment of mitochondrion localization

GO:0051856

adhesion to symbiont

GO:0060370

susceptibility to T cell mediated cytotoxicity