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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG003947

Entrez Gene ID

5831

Official Gene Symbol

PYCR1

Synonyms

ARCL2B|P5C|P5CR|PIG45|PP222|PRO3|PYCR

Gene name

pyrroline-5-carboxylate reductase 1

Gene Type

protein-coding

Chromosome

17

Genomics Location

17q25.3

Protein products

Pyrroline-5-carboxylate reductase

Pyrroline-5-carboxylate reductase 1, mitochondrial

Putative uncharacterized protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9721
MIM:179035
Ensembl:ENSG00000183010
HPRD:01528
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004735

pyrroline-5-carboxylate reductase activity

GO:0005488

binding

GO:0005739

mitochondrion

GO:0005759

mitochondrial matrix

GO:0006561

proline biosynthetic process

GO:0006950

response to stress

GO:0008652

cellular amino acid biosynthetic process

GO:0016491

oxidoreductase activity

GO:0034599

cellular response to oxidative stress

GO:0034641

cellular nitrogen compound metabolic process