Gene basic information
| LiverAtlas Gene ID |
HuLG003974 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
RAC1 |
|
Synonyms |
MGC111543|TCN25|p21NRac1 |
|
Gene name |
ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
|
Gene Type |
protein-coding |
|
Chromosome |
7 |
|
Genomics Location |
7p22 |
|
Known cancer genes |
Yes |
|
Protein products |
Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1) Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1) Ras-related C3 botulinum toxin substrate 1 (Rho family, small GTP binding protein Rac1) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:9801
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000166 |
nucleotide binding |
|
GO:0003924 |
GTPase activity |
|
GO:0005515 |
protein binding |
|
GO:0005525 |
GTP binding |
|
GO:0005622 |
intracellular |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0006184 |
GTP catabolic process |
|
GO:0006915 |
apoptosis |
|
GO:0006928 |
cellular component movement |
|
GO:0006954 |
inflammatory response |
|
GO:0007155 |
cell adhesion |
|
GO:0007160 |
cell-matrix adhesion |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0007411 |
axon guidance |
|
GO:0007596 |
blood coagulation |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0009611 |
response to wounding |
|
GO:0009653 |
anatomical structure morphogenesis |
|
GO:0010310 |
regulation of hydrogen peroxide metabolic process |
|
GO:0010592 |
positive regulation of lamellipodium assembly |
|
GO:0016032 |
viral reproduction |
|
GO:0019899 |
enzyme binding |
|
GO:0030032 |
lamellipodium assembly |
|
GO:0030041 |
actin filament polymerization |
|
GO:0030168 |
platelet activation |
|
GO:0030334 |
regulation of cell migration |
|
GO:0030742 |
GTP-dependent protein binding |
|
GO:0031295 |
T cell costimulation |
|
GO:0031529 |
ruffle organization |
|
GO:0031996 |
thioesterase binding |
|
GO:0032707 |
negative regulation of interleukin-23 production |
|
GO:0035025 |
positive regulation of Rho protein signal transduction |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0042470 |
melanosome |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0048261 |
negative regulation of receptor-mediated endocytosis |
|
GO:0048870 |
cell motility |
|
GO:0050690 |
regulation of defense response to virus by virus |
|
GO:0051056 |
regulation of small GTPase mediated signal transduction |
|
GO:0051668 |
localization within membrane |
|
GO:0060263 |
regulation of respiratory burst |
