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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004012

Entrez Gene ID

5921

Official Gene Symbol

RASA1

Synonyms

CMNAVM|CMAVM|DKFZp434N071|GAP|PKWS|RASA|RASGAP|p120GAP|p120RASGAP

Gene name

RAS p21 protein activator (GTPase activating protein) 1

Gene Type

protein-coding

Chromosome

5

Genomics Location

5q13.3

Known cancer genes

Yes

Protein products

RASA1 protein

RASA1 protein

Ras GTPase-activating protein 1

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:9871
MIM:139150
Ensembl:ENSG00000145715
HPRD:00745
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000910

cytokinesis

GO:0001570

vasculogenesis

GO:0001726

ruffle

GO:0001948

glycoprotein binding

GO:0001953

negative regulation of cell-matrix adhesion

GO:0005099

Ras GTPase activator activity

GO:0005102

receptor binding

GO:0005515

protein binding

GO:0005622

intracellular

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005886

plasma membrane

GO:0007162

negative regulation of cell adhesion

GO:0007165

signal transduction

GO:0008360

regulation of cell shape

GO:0009790

embryo development

GO:0019870

potassium channel inhibitor activity

GO:0030833

regulation of actin filament polymerization

GO:0031235

intrinsic to internal side of plasma membrane

GO:0032320

positive regulation of Ras GTPase activity

GO:0035556

intracellular signal transduction

GO:0043524

negative regulation of neuron apoptosis

GO:0045768

positive regulation of anti-apoptosis

GO:0046580

negative regulation of Ras protein signal transduction

GO:0051020

GTPase binding

GO:0051056

regulation of small GTPase mediated signal transduction

GO:0051252

regulation of RNA metabolic process