Gene basic information
| LiverAtlas Gene ID |
HuLG004113 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ROCK1 |
|
Synonyms |
MGC131603|MGC43611|P160ROCK|PRO0435 |
|
Gene name |
Rho-associated, coiled-coil containing protein kinase 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
18 |
|
Genomics Location |
18q11.1 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:10251
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000139 |
Golgi membrane |
|
GO:0000166 |
nucleotide binding |
|
GO:0000910 |
cytokinesis |
|
GO:0004672 |
protein kinase activity |
|
GO:0004674 |
protein serine/threonine kinase activity |
|
GO:0005515 |
protein binding |
|
GO:0005524 |
ATP binding |
|
GO:0005622 |
intracellular |
|
GO:0005737 |
cytoplasm |
|
GO:0005794 |
Golgi apparatus |
|
GO:0005814 |
centriole |
|
GO:0005829 |
cytosol |
|
GO:0005856 |
cytoskeleton |
|
GO:0006468 |
protein phosphorylation |
|
GO:0006915 |
apoptosis |
|
GO:0006921 |
cellular component disassembly involved in apoptosis |
|
GO:0007159 |
leukocyte cell-cell adhesion |
|
GO:0007165 |
signal transduction |
|
GO:0007266 |
Rho protein signal transduction |
|
GO:0007411 |
axon guidance |
|
GO:0016020 |
membrane |
|
GO:0017049 |
GTP-Rho binding |
|
GO:0022614 |
membrane to membrane docking |
|
GO:0030036 |
actin cytoskeleton organization |
|
GO:0032060 |
bleb assembly |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0042802 |
identical protein binding |
|
GO:0043524 |
negative regulation of neuron apoptosis |
|
GO:0046872 |
metal ion binding |
|
GO:0050900 |
leukocyte migration |
|
GO:0050901 |
leukocyte tethering or rolling |
