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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004115

Entrez Gene ID

6095

Official Gene Symbol

RORA

Synonyms

DKFZp686M2414|MGC119326|MGC119329|NR1F1|ROR1|ROR2|ROR3|RZRNALPHA|RZRA

Gene name

RAR-related orphan receptor A

Gene Type

protein-coding

Chromosome

15

Genomics Location

15q22.2

Known cancer genes

Yes

Protein products

Retinoid-related orphan receptor alpha

Nuclear receptor ROR-alpha

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:10258
MIM:600825
Ensembl:ENSG00000069667
HPRD:02896
RefSeq Genomic nucleotide accession:AC_000058
RefSeq Genomic nucleotide gi:89161193

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0003700

sequence-specific DNA binding transcription factor activity

GO:0003707

steroid hormone receptor activity

GO:0004879

ligand-dependent nuclear receptor activity

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0006351

transcription, DNA-dependent

GO:0006355

regulation of transcription, DNA-dependent

GO:0006809

nitric oxide biosynthetic process

GO:0007165

signal transduction

GO:0008270

zinc ion binding

GO:0010467

gene expression

GO:0021702

cerebellar Purkinje cell differentiation

GO:0034339

regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor

GO:0043030

regulation of macrophage activation

GO:0043565

sequence-specific DNA binding

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

GO:0046068

cGMP metabolic process

GO:0046872

metal ion binding