HuLG004123

Entrez Gene ID

6117

Official Gene Symbol

RPA1

Synonyms

HSSB|MST075|REPA1|RFNA|RPNA|RPA70

Gene name

replication protein A1, 70kDa

Gene Type

protein-coding

Chromosome

17

Genomics Location

17p13.3

Known cancer genes

Yes

Protein products

MSTP075

Replication protein A 70 kDa DNA-binding subunit

Related liver disease name

Hepatitis C

Hepatocellular carcinoma

Database cross reference

HGNC:10289
MIM:179835
Ensembl:ENSG00000132383
HPRD:01565
RefSeq Genomic nucleotide accession:AC_000060
RefSeq Genomic nucleotide gi:89161195

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

GO annotation

GO:0000075

cell cycle checkpoint

GO:0000082

G1/S transition of mitotic cell cycle

GO:0000084

S phase of mitotic cell cycle

GO:0000216

M/G1 transition of mitotic cell cycle

GO:0000278

mitotic cell cycle

GO:0000718

nucleotide-excision repair, DNA damage removal

GO:0000722

telomere maintenance via recombination

GO:0000723

telomere maintenance

GO:0000724

double-strand break repair via homologous recombination

GO:0000730

DNA recombinase assembly

GO:0003677

DNA binding

GO:0003697

single-stranded DNA binding

GO:0005515

protein binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005662

DNA replication factor A complex

GO:0005730

nucleolus

GO:0005737

cytoplasm

GO:0006260

DNA replication

GO:0006261

DNA-dependent DNA replication

GO:0006271

DNA strand elongation involved in DNA replication

GO:0006281

DNA repair

GO:0006283

transcription-coupled nucleotide-excision repair

GO:0006289

nucleotide-excision repair

GO:0006297

nucleotide-excision repair, DNA gap filling

GO:0006302

double-strand break repair

GO:0006310

DNA recombination

GO:0015629

actin cytoskeleton

GO:0016605

PML body

GO:0032201

telomere maintenance via semi-conservative replication

GO:0046872

metal ion binding