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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004184

Entrez Gene ID

6197

Official Gene Symbol

RPS6KA3

Synonyms

CLS|HUN3|ISPKN1|MAPKAPK1B|MRX19|RSK|RSK2|S6KNalpha3|p90NRSK2|pp90RSK2

Gene name

ribosomal protein S6 kinase, 90kDa, polypeptide 3

Gene Type

protein-coding

Chromosome

0

Genomics Location

Xp22.2-p22.1

Known cancer genes

Yes

Protein products

Ribosomal protein S6 kinase, 90kDa, polypeptide 3

Ribosomal protein S6 kinase alpha-3

RPS6KA3 protein

RPS6KA3 protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:10432
MIM:300075
Ensembl:ENSG00000177189
HPRD:02092
RefSeq Genomic nucleotide accession:AC_000066
RefSeq Genomic nucleotide gi:89161217

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000166

nucleotide binding

GO:0000287

magnesium ion binding

GO:0001501

skeletal system development

GO:0002224

toll-like receptor signaling pathway

GO:0002755

MyD88-dependent toll-like receptor signaling pathway

GO:0002756

MyD88-independent toll-like receptor signaling pathway

GO:0004672

protein kinase activity

GO:0004674

protein serine/threonine kinase activity

GO:0005524

ATP binding

GO:0005634

nucleus

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006468

protein phosphorylation

GO:0007165

signal transduction

GO:0007243

intracellular protein kinase cascade

GO:0007268

synaptic transmission

GO:0007411

axon guidance

GO:0007417

central nervous system development

GO:0008063

Toll signaling pathway

GO:0016301

kinase activity

GO:0016310

phosphorylation

GO:0034130

toll-like receptor 1 signaling pathway

GO:0034134

toll-like receptor 2 signaling pathway

GO:0034138

toll-like receptor 3 signaling pathway

GO:0034142

toll-like receptor 4 signaling pathway

GO:0043027

caspase inhibitor activity

GO:0043154

negative regulation of caspase activity

GO:0045087

innate immune response

GO:0048011

nerve growth factor receptor signaling pathway

GO:0051403

stress-activated MAPK cascade