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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004215

Entrez Gene ID

6240

Official Gene Symbol

RRM1

Synonyms

R1|RIR1|RR1

Gene name

ribonucleotide reductase M1

Gene Type

protein-coding

Chromosome

11

Genomics Location

11p15.5

Known cancer genes

Yes

Protein products

Ribonucleoside-diphosphate reductase large subunit

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:10451
MIM:180410
Ensembl:ENSG00000167325
HPRD:01588
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004748

ribonucleoside-diphosphate reductase activity

GO:0005524

ATP binding

GO:0005654

nucleoplasm

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0005971

ribonucleoside-diphosphate reductase complex

GO:0006260

DNA replication

GO:0009263

deoxyribonucleotide biosynthetic process

GO:0015949

nucleobase, nucleoside and nucleotide interconversion

GO:0016491

oxidoreductase activity

GO:0017076

purine nucleotide binding

GO:0051259

protein oligomerization

GO:0051290

protein heterotetramerization

GO:0055086

nucleobase, nucleoside and nucleotide metabolic process