HuLG004284

Entrez Gene ID

6337

Official Gene Symbol

SCNN1A

Synonyms

BESC2|ENaCa|ENaCalpha|FLJ21883|SCNEA|SCNN1

Gene name

sodium channel, nonvoltage-gated 1 alpha

Gene Type

protein-coding

Chromosome

12

Genomics Location

12p13

Known cancer genes

Yes

Protein products

cDNA FLJ56208, highly similar to Amiloride-sensitive sodium channel subunit alpha

Amiloride-sensitive sodium channel subunit alpha 1

Amiloride-sensitive epithelial sodium channel alpha subunit

Amiloride-sensitive sodium channel subunit alpha

Related liver disease name

Liver fibrosis and liver cirrhosis

Database cross reference

HGNC:10599
MIM:600228
Ensembl:ENSG00000111319
HPRD:02575
RefSeq Genomic nucleotide accession:AC_000055
RefSeq Genomic nucleotide gi:89161189

GO annotation

GO:0003779

actin binding

GO:0005216

ion channel activity

GO:0005515

protein binding

GO:0005624

membrane fraction

GO:0005886

plasma membrane

GO:0006811

ion transport

GO:0006814

sodium ion transport

GO:0007588

excretion

GO:0009897

external side of plasma membrane

GO:0015280

ligand-gated sodium channel activity

GO:0016021

integral to membrane

GO:0016324

apical plasma membrane

GO:0030864

cortical actin cytoskeleton

GO:0034706

sodium channel complex

GO:0050699

WW domain binding

GO:0050896

response to stimulus

GO:0050909

sensory perception of taste