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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004324

Entrez Gene ID

6387

Official Gene Symbol

CXCL12

Synonyms

IRH|PBSF|SCYB12|SDF1|SDF1A|SDF1B|TLSF|TPAR1

Gene name

chemokine (C-X-C motif) ligand 12

Gene Type

protein-coding

Chromosome

10

Genomics Location

10q11.1

Known cancer genes

Yes

Protein products

Stromal cell-derived factor 1 delta

CXCL12 protein

Stromal cell-derived factor 1

Related liver disease name

Hepatitis

Liver fibrosis and liver cirrhosis

Viral hepatitis

Hepatitis A

Hepatitis B

Hepatitis C

Chronic hepatitis C

Hepatitis D

Hepatitis E

Chronic hepatitis

Alcoholic liver cirrhosis

Hepatocellular carcinoma

Intrahepatic cholangiocarcinoma

Hepatocellular carcinoma

Nonalcoholic steatohepatitis

Database cross reference

HGNC:10672
MIM:600835
Ensembl:ENSG00000107562
HPRD:02904
RefSeq Genomic nucleotide accession:AC_000053
RefSeq Genomic nucleotide gi:89161186

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net OncoDB

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0004871

signal transducer activity

GO:0005102

receptor binding

GO:0005576

extracellular region

GO:0005615

extracellular space

GO:0006874

cellular calcium ion homeostasis

GO:0006935

chemotaxis

GO:0006955

immune response

GO:0007155

cell adhesion

GO:0007165

signal transduction

GO:0007186

G-protein coupled receptor protein signaling pathway

GO:0008009

chemokine activity

GO:0008015

blood circulation

GO:0008064

regulation of actin polymerization or depolymerization

GO:0008083

growth factor activity

GO:0009615

response to virus

GO:0090026

positive regulation of monocyte chemotaxis

GO:2000107

negative regulation of leukocyte apoptosis