Gene basic information
| LiverAtlas Gene ID |
HuLG004327 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SDHB |
|
Synonyms |
FLJ92337|IP|PGL4|SDH|SDH1|SDH2|SDHIP |
|
Gene name |
succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1p36.1-p35 |
|
Known cancer genes |
Yes |
|
Protein products |
Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial Succinate dehydrogenase complex subunit B Succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:10681
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005515 |
protein binding |
|
GO:0005739 |
mitochondrion |
|
GO:0005743 |
mitochondrial inner membrane |
|
GO:0005749 |
mitochondrial respiratory chain complex II |
|
GO:0006099 |
tricarboxylic acid cycle |
|
GO:0006105 |
succinate metabolic process |
|
GO:0006810 |
transport |
|
GO:0008177 |
succinate dehydrogenase (ubiquinone) activity |
|
GO:0009055 |
electron carrier activity |
|
GO:0009060 |
aerobic respiration |
|
GO:0016020 |
membrane |
|
GO:0016491 |
oxidoreductase activity |
|
GO:0022904 |
respiratory electron transport chain |
|
GO:0046872 |
metal ion binding |
|
GO:0048039 |
ubiquinone binding |
|
GO:0051537 |
2 iron, 2 sulfur cluster binding |
|
GO:0051538 |
3 iron, 4 sulfur cluster binding |
|
GO:0051539 |
4 iron, 4 sulfur cluster binding |
