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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004328

Entrez Gene ID

6391

Official Gene Symbol

SDHC

Synonyms

CYB560|CYBL|PGL3|QPS1|SDH3

Gene name

succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa

Gene Type

protein-coding

Chromosome

1

Genomics Location

1q23.3

Known cancer genes

Yes

Protein products

Succinate dehydrogenase cytochrome b560 subunit, mitochondrial

Succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa, isoform CRA a

Integral membrane protein CII-3b

Succinate dehydrogenase complex, subunit C delta5 alternative splicing variant

Succinate dehydrogenase complex, subunit C delta2+3 alternative splicing variant

SDHC protein

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:10682
MIM:602413
Ensembl:ENSG00000143252
HPRD:03878
RefSeq Genomic nucleotide accession:AC_000044
RefSeq Genomic nucleotide gi:89161184

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0000104

succinate dehydrogenase activity

GO:0005739

mitochondrion

GO:0005743

mitochondrial inner membrane

GO:0005749

mitochondrial respiratory chain complex II

GO:0006099

tricarboxylic acid cycle

GO:0006810

transport

GO:0009055

electron carrier activity

GO:0009060

aerobic respiration

GO:0016020

membrane

GO:0016021

integral to membrane

GO:0020037

heme binding

GO:0022904

respiratory electron transport chain

GO:0045273

respiratory chain complex II

GO:0045282

plasma membrane succinate dehydrogenase complex

GO:0046872

metal ion binding

GO:0055114

oxidation-reduction process