Gene basic information
| LiverAtlas Gene ID |
HuLG004349 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SFRP2 |
|
Synonyms |
FRPN2|SARP1|SDFN5 |
|
Gene name |
secreted frizzled-related protein 2 |
|
Gene Type |
protein-coding |
|
Chromosome |
4 |
|
Genomics Location |
4q31.3 |
|
Known cancer genes |
Yes |
|
Protein products |
cDNA FLJ36603 fis, clone TRACH2015180, highly similar to Secreted frizzled-related protein 2 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:10777
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0001569 |
patterning of blood vessels |
|
GO:0001843 |
neural tube closure |
|
GO:0001944 |
vasculature development |
|
GO:0001968 |
fibronectin binding |
|
GO:0002063 |
chondrocyte development |
|
GO:0003151 |
outflow tract morphogenesis |
|
GO:0003214 |
cardiac left ventricle morphogenesis |
|
GO:0005178 |
integrin binding |
|
GO:0005576 |
extracellular region |
|
GO:0005615 |
extracellular space |
|
GO:0005737 |
cytoplasm |
|
GO:0005886 |
plasma membrane |
|
GO:0007267 |
cell-cell signaling |
|
GO:0007420 |
brain development |
|
GO:0007584 |
response to nutrient |
|
GO:0008219 |
cell death |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008285 |
negative regulation of cell proliferation |
|
GO:0008406 |
gonad development |
|
GO:0008584 |
male gonad development |
|
GO:0009790 |
embryo development |
|
GO:0010577 |
metalloenzyme activator activity |
|
GO:0010629 |
negative regulation of gene expression |
|
GO:0010667 |
negative regulation of cardiac muscle cell apoptosis |
|
GO:0010719 |
negative regulation of epithelial to mesenchymal transition |
|
GO:0017147 |
Wnt-protein binding |
|
GO:0021915 |
neural tube development |
|
GO:0030154 |
cell differentiation |
|
GO:0030165 |
PDZ domain binding |
|
GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
|
GO:0030199 |
collagen fibril organization |
|
GO:0030307 |
positive regulation of cell growth |
|
GO:0030308 |
negative regulation of cell growth |
|
GO:0030336 |
negative regulation of cell migration |
|
GO:0030514 |
negative regulation of BMP signaling pathway |
|
GO:0031012 |
extracellular matrix |
|
GO:0031668 |
cellular response to extracellular stimulus |
|
GO:0033138 |
positive regulation of peptidyl-serine phosphorylation |
|
GO:0033630 |
positive regulation of cell adhesion mediated by integrin |
|
GO:0035121 |
tail morphogenesis |
|
GO:0042493 |
response to drug |
|
GO:0042662 |
negative regulation of mesodermal cell fate specification |
|
GO:0042733 |
embryonic digit morphogenesis |
|
GO:0042813 |
Wnt receptor activity |
|
GO:0042995 |
cell projection |
|
GO:0043065 |
positive regulation of apoptosis |
|
GO:0043066 |
negative regulation of apoptosis |
|
GO:0043154 |
negative regulation of caspase activity |
|
GO:0043508 |
negative regulation of JUN kinase activity |
|
GO:0045600 |
positive regulation of fat cell differentiation |
|
GO:0045669 |
positive regulation of osteoblast differentiation |
|
GO:0045766 |
positive regulation of angiogenesis |
|
GO:0045768 |
positive regulation of anti-apoptosis |
|
GO:0045892 |
negative regulation of transcription, DNA-dependent |
|
GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
|
GO:0048018 |
receptor agonist activity |
|
GO:0048546 |
digestive tract morphogenesis |
|
GO:0050680 |
negative regulation of epithelial cell proliferation |
|
GO:0050732 |
negative regulation of peptidyl-tyrosine phosphorylation |
|
GO:0051216 |
cartilage development |
|
GO:0060028 |
convergent extension involved in axis elongation |
|
GO:0060349 |
bone morphogenesis |
|
GO:0061054 |
dermatome development |
|
GO:0061056 |
sclerotome development |
|
GO:0061133 |
endopeptidase activator activity |
|
GO:0071425 |
hemopoietic stem cell proliferation |
|
GO:0071481 |
cellular response to X-ray |
|
GO:0090090 |
negative regulation of canonical Wnt receptor signaling pathway |
|
GO:0090175 |
regulation of establishment of planar polarity |
|
GO:0090179 |
planar cell polarity pathway involved in neural tube closure |
|
GO:0090244 |
Wnt receptor signaling pathway involved in somitogenesis |
|
GO:0090263 |
positive regulation of canonical Wnt receptor signaling pathway |
|
GO:2000035 |
regulation of stem cell division |
|
GO:2000041 |
negative regulation of planar cell polarity pathway involved in axis elongation |
