Gene basic information
| LiverAtlas Gene ID |
HuLG004375 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
ITSN1 |
|
Synonyms |
ITSN|MGC134948|MGC134949|SH3D1A|SH3P17 |
|
Gene name |
intersectin 1 (SH3 domain protein) |
|
Gene Type |
protein-coding |
|
Chromosome |
21 |
|
Genomics Location |
21q22.1-q22.2 |
|
Known cancer genes |
Yes |
|
Protein products |
Intersectin 1 short form variant 3 Intersectin 1 short form variant 7 |
|
Database cross reference |
HGNC:6183
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0005085 |
guanyl-nucleotide exchange factor activity |
|
GO:0005089 |
Rho guanyl-nucleotide exchange factor activity |
|
GO:0005509 |
calcium ion binding |
|
GO:0005515 |
protein binding |
|
GO:0005622 |
intracellular |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0005905 |
coated pit |
|
GO:0006915 |
apoptosis |
|
GO:0007264 |
small GTPase mediated signal transduction |
|
GO:0008624 |
induction of apoptosis by extracellular signals |
|
GO:0019209 |
kinase activator activity |
|
GO:0019717 |
synaptosome |
|
GO:0030027 |
lamellipodium |
|
GO:0030054 |
cell junction |
|
GO:0030139 |
endocytic vesicle |
|
GO:0032947 |
protein complex scaffold |
|
GO:0035023 |
regulation of Rho protein signal transduction |
|
GO:0043524 |
negative regulation of neuron apoptosis |
|
GO:0045202 |
synapse |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0048488 |
synaptic vesicle endocytosis |
|
GO:0051056 |
regulation of small GTPase mediated signal transduction |
|
GO:0051897 |
positive regulation of protein kinase B signaling cascade |
|
GO:0070064 |
proline-rich region binding |
