Gene basic information
| LiverAtlas Gene ID |
HuLG004383 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SHC1 |
|
Synonyms |
FLJ26504|SHC|SHCA |
|
Gene name |
SHC (Src homology 2 domain containing) transforming protein 1 |
|
Gene Type |
protein-coding |
|
Chromosome |
1 |
|
Genomics Location |
1q21 |
|
Known cancer genes |
Yes |
|
Protein products |
SHC (Src homology 2 domain containing) transforming protein 1 |
|
Related liver disease name |
|
|
Database cross reference |
HGNC:10840
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net OncoDB |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000165 |
MAPKKK cascade |
|
GO:0000187 |
activation of MAPK activity |
|
GO:0001525 |
angiogenesis |
|
GO:0001666 |
response to hypoxia |
|
GO:0001784 |
phosphotyrosine binding |
|
GO:0005068 |
transmembrane receptor protein tyrosine kinase adaptor activity |
|
GO:0005154 |
epidermal growth factor receptor binding |
|
GO:0005158 |
insulin receptor binding |
|
GO:0005159 |
insulin-like growth factor receptor binding |
|
GO:0005515 |
protein binding |
|
GO:0005543 |
phospholipid binding |
|
GO:0005634 |
nucleus |
|
GO:0005737 |
cytoplasm |
|
GO:0005739 |
mitochondrion |
|
GO:0005759 |
mitochondrial matrix |
|
GO:0005829 |
cytosol |
|
GO:0005886 |
plasma membrane |
|
GO:0007173 |
epidermal growth factor receptor signaling pathway |
|
GO:0007176 |
regulation of epidermal growth factor receptor activity |
|
GO:0007265 |
Ras protein signal transduction |
|
GO:0007507 |
heart development |
|
GO:0007568 |
aging |
|
GO:0007596 |
blood coagulation |
|
GO:0008284 |
positive regulation of cell proliferation |
|
GO:0008286 |
insulin receptor signaling pathway |
|
GO:0008543 |
fibroblast growth factor receptor signaling pathway |
|
GO:0009636 |
response to toxin |
|
GO:0010008 |
endosome membrane |
|
GO:0016337 |
cell-cell adhesion |
|
GO:0030182 |
neuron differentiation |
|
GO:0031100 |
organ regeneration |
|
GO:0031175 |
neuron projection development |
|
GO:0031532 |
actin cytoskeleton reorganization |
|
GO:0032868 |
response to insulin stimulus |
|
GO:0035094 |
response to nicotine |
|
GO:0035556 |
intracellular signal transduction |
|
GO:0040008 |
regulation of growth |
|
GO:0042542 |
response to hydrogen peroxide |
|
GO:0045740 |
positive regulation of DNA replication |
|
GO:0045907 |
positive regulation of vasoconstriction |
|
GO:0048011 |
nerve growth factor receptor signaling pathway |
|
GO:0048661 |
positive regulation of smooth muscle cell proliferation |
|
GO:0050900 |
leukocyte migration |
|
GO:0051219 |
phosphoprotein binding |
|
GO:0051384 |
response to glucocorticoid stimulus |
|
GO:0070435 |
Shc-EGFR complex |
