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LiverAtlas Gene ID	HuLG004386
Entrez Gene ID	6470
Official Gene Symbol	SHMT1
Synonyms	CSHMT\|MGC15229\|MGC24556\|SHMT
Gene name	serine hydroxymethyltransferase 1 (soluble)
Gene Type	protein-coding
Chromosome	17
Genomics Location	17p11.2
Known cancer genes	Yes
Protein products	Uncharacterized protein Serine hydroxymethyltransferase Serine hydroxymethyltransferase, cytosolic Cytosolic serine hydroxymethyltransferase Cytosolic serine hydroxymethyltransferase
Related liver disease name	Hepatocellular carcinoma
Database cross reference	HGNC:10850 MIM:182144 Ensembl:ENSG00000176974 HPRD:01643 RefSeq Genomic nucleotide accession:AC_000060 RefSeq Genomic nucleotide gi:89161195

GO ID	GO annotation
GO:0004372	glycine hydroxymethyltransferase activity
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005829	cytosol
GO:0006565	L-serine catabolic process
GO:0006730	one-carbon metabolic process
GO:0006766	vitamin metabolic process
GO:0006767	water-soluble vitamin metabolic process
GO:0008732	L-allo-threonine aldolase activity
GO:0009113	purine base biosynthetic process
GO:0016597	amino acid binding
GO:0016740	transferase activity
GO:0019264	glycine biosynthetic process from serine
GO:0030170	pyridoxal phosphate binding
GO:0034641	cellular nitrogen compound metabolic process
GO:0042803	protein homodimerization activity
GO:0045329	carnitine biosynthetic process
GO:0046655	folic acid metabolic process
GO:0051262	protein tetramerization
GO:0051289	protein homotetramerization