HuLG004392

Entrez Gene ID

6478

Official Gene Symbol

SIAH2

Synonyms

hSiah2

Gene name

seven in absentia homolog 2 (Drosophila)

Gene Type

protein-coding

Chromosome

3

Genomics Location

3q25

Known cancer genes

Yes

Protein products

Alpha(1,2)fucosyltransferase

E3 ubiquitin-protein ligase SIAH2

Database cross reference

HGNC:10858
MIM:602213
Ensembl:ENSG00000181788
HPRD:03737
RefSeq Genomic nucleotide accession:AC_000046
RefSeq Genomic nucleotide gi:89161204

GO annotation

GO:0003714

transcription corepressor activity

GO:0004842

ubiquitin-protein ligase activity

GO:0005634

nucleus

GO:0005737

cytoplasm

GO:0005829

cytosol

GO:0006511

ubiquitin-dependent protein catabolic process

GO:0006915

apoptosis

GO:0007049

cell cycle

GO:0007264

small GTPase mediated signal transduction

GO:0007275

multicellular organismal development

GO:0007411

axon guidance

GO:0008270

zinc ion binding

GO:0016874

ligase activity

GO:0044257

cellular protein catabolic process

GO:0046872

metal ion binding

GO:0090090

negative regulation of canonical Wnt receptor signaling pathway