Gene basic information
| LiverAtlas Gene ID |
HuLG004410 |
|
Entrez Gene ID |
|
|
Official Gene Symbol |
SKP2 |
|
Synonyms |
FBL1|FBXL1|FLB1|MGC1366 |
|
Gene name |
S-phase kinase-associated protein 2 (p45) |
|
Gene Type |
protein-coding |
|
Chromosome |
5 |
|
Genomics Location |
5p13 |
|
Known cancer genes |
Yes |
|
Protein products |
|
|
Related liver disease name |
|
|
Database cross reference |
HGNC:10901
|
Liver relevance
|
HCC significant genes |
Yes/No |
Yes |
|
Evidence |
EHCO HCC.net |
|
|
Quality score |
|
Ontology annotation
| GO ID |
GO annotation |
|
GO:0000082 |
G1/S transition of mitotic cell cycle |
|
GO:0000084 |
S phase of mitotic cell cycle |
|
GO:0000086 |
G2/M transition of mitotic cell cycle |
|
GO:0000209 |
protein polyubiquitination |
|
GO:0000278 |
mitotic cell cycle |
|
GO:0004842 |
ubiquitin-protein ligase activity |
|
GO:0005515 |
protein binding |
|
GO:0005654 |
nucleoplasm |
|
GO:0006511 |
ubiquitin-dependent protein catabolic process |
|
GO:0008283 |
cell proliferation |
|
GO:0008634 |
negative regulation of survival gene product expression |
|
GO:0019005 |
SCF ubiquitin ligase complex |
|
GO:0031145 |
anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process |
|
GO:0033148 |
positive regulation of estrogen receptor signaling pathway |
|
GO:0051726 |
regulation of cell cycle |
