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Gene, Transcriptome, Protein, Pathway or Disease. 

Gene basic information

LiverAtlas Gene ID

HuLG004414

Entrez Gene ID

6506

Official Gene Symbol

SLC1A2

Synonyms

EAAT2|GLTN1

Gene name

solute carrier family 1 (glial high affinity glutamate transporter), member 2

Gene Type

protein-coding

Chromosome

11

Genomics Location

11p13-p12

Known cancer genes

Yes

Protein products

Solute carrier family 1 (Glial high affinity glutamate transporter), member 2

Excitatory amino acid transporter 2

Related liver disease name

Hepatocellular carcinoma

Database cross reference

HGNC:10940
MIM:600300
Ensembl:ENSG00000110436
HPRD:02625
RefSeq Genomic nucleotide accession:AC_000054
RefSeq Genomic nucleotide gi:89161188

Liver relevance

HCC significant genes

Yes/No

Yes

Evidence

EHCO HCC.net

Quality score

 

Ontology annotation

GO ID

GO annotation

GO:0005313

L-glutamate transmembrane transporter activity

GO:0005314

high-affinity glutamate transmembrane transporter activity

GO:0005624

membrane fraction

GO:0005886

plasma membrane

GO:0006811

ion transport

GO:0006835

dicarboxylic acid transport

GO:0007268

synaptic transmission

GO:0007399

nervous system development

GO:0007632

visual behavior

GO:0009611

response to wounding

GO:0010259

multicellular organismal aging

GO:0015293

symporter activity

GO:0015501

glutamate:sodium symporter activity

GO:0015813

L-glutamate transport

GO:0016021

integral to membrane

GO:0017153

sodium:dicarboxylate symporter activity

GO:0021537

telencephalon development

GO:0030424

axon

GO:0030534

adult behavior

GO:0030673

axolemma

GO:0031668

cellular response to extracellular stimulus

GO:0035264

multicellular organism growth

GO:0042493

response to drug

GO:0042734

presynaptic membrane

GO:0043197

dendritic spine

GO:0043198

dendritic shaft

GO:0043200

response to amino acid stimulus

GO:0045202

synapse

GO:0046326

positive regulation of glucose import

GO:0051938

L-glutamate import

GO:0055085

transmembrane transport

GO:0070779

D-aspartate import