HuLG004438

Entrez Gene ID

6531

Official Gene Symbol

SLC6A3

Synonyms

DAT|DAT1

Gene name

solute carrier family 6 (neurotransmitter transporter, dopamine), member 3

Gene Type

protein-coding

Chromosome

5

Genomics Location

5p15.3

Known cancer genes

Yes

Protein products

Transporter

Dopamine transporter

Sodium-dependent dopamine transporter

Related liver disease name

Alcoholic liver cirrhosis

Database cross reference

HGNC:11049
MIM:126455
Ensembl:ENSG00000142319
HPRD:00543
RefSeq Genomic nucleotide accession:AC_000048
RefSeq Genomic nucleotide gi:89161208

GO annotation

GO:0005102

receptor binding

GO:0005329

dopamine transmembrane transporter activity

GO:0005330

dopamine:sodium symporter activity

GO:0005737

cytoplasm

GO:0005886

plasma membrane

GO:0005887

integral to plasma membrane

GO:0006810

transport

GO:0006836

neurotransmitter transport

GO:0007268

synaptic transmission

GO:0007568

aging

GO:0007595

lactation

GO:0007608

sensory perception of smell

GO:0007626

locomotory behavior

GO:0008144

drug binding

GO:0008219

cell death

GO:0008504

monoamine transmembrane transporter activity

GO:0010039

response to iron ion

GO:0015293

symporter activity

GO:0015844

monoamine transport

GO:0015872

dopamine transport

GO:0016021

integral to membrane

GO:0019717

synaptosome

GO:0021984

adenohypophysis development

GO:0030424

axon

GO:0032403

protein complex binding

GO:0035094

response to nicotine

GO:0035240

dopamine binding

GO:0040018

positive regulation of multicellular organism growth

GO:0042053

regulation of dopamine metabolic process

GO:0042136

neurotransmitter biosynthetic process

GO:0042220

response to cocaine

GO:0042416

dopamine biosynthetic process

GO:0042420

dopamine catabolic process

GO:0042493

response to drug

GO:0043025

neuronal cell body

GO:0045471

response to ethanol

GO:0047485

protein N-terminus binding

GO:0051591

response to cAMP

GO:0055085

transmembrane transport

GO:0060134

prepulse inhibition